Molecular characterization of the grape seeds extract's effect against chemically induced liver cancer: In vivo and in vitro analyses

AA Hamza, GH Heeba, HM Elwy, C Murali… - Scientific reports, 2018 - nature.com
… The initiationpromotion model of cancer development used … The initiation stage of cancer
development can be produced by … If rats are older than 2 weeks, a tumor promoter is required …

[HTML][HTML] Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/inflammation …

AA Hamza, GH Heeba, S Hamza, A Abdalla… - Biomedicine & …, 2021 - Elsevier
… -preventative impact on liver cancer by inhibiting the growth of … The initiationpromotion
model of cancer development used in … model of HCC in rats induced by DEN and promoted by 2-…

Saffron-based crocin prevents early lesions of liver cancer: in vivo, in vitro and network analyses

A Amin, AA Hamza, S Daoud… - … on Anti-Cancer Drug …, 2016 - ingentaconnect.com
action of saffron’s main biomolecule, crocin, against chemically-induced liver cancer in rats,
… In this study, the initiation-promotion DEN-induced cancer model used mimiced the early …

[HTML][HTML] Potential effect of exosomes derived from cancer stem cells and MSCs on progression of DEN-induced HCC in rats

FA Alzahrani, MA El-Magd… - Stem Cells …, 2018 - hindawi.com
… a tumor stimulatory effect (induction of tumor growth, … have a key role in tumor initiation and
maintenance but also may … on the promotion stage of hepatocarcinogenesis in rats,” Food …

Wnt–β-catenin signalling in liver development, health and disease

MJ Perugorria, P Olaizola, I Labiano… - Nature reviews …, 2019 - nature.com
… of action and regulation of Wnt–β-catenin signalling in liver … uncommitted endoderm to
initiate the expression of HHEX. … -001 also reduced tumour growth in mice and rat models 131 . …

A small plant with big benefits: Fenugreek (Trigonella foenum‐graecum Linn.) for disease prevention and health promotion

KC Nagulapalli Venkata, A Swaroop… - Molecular nutrition & …, 2017 - Wiley Online Library
promoting the insulin-sensitizing effects. It does by increasing glucose utilization and
decreasing hepatic glucose synthesis in obese rats … (DMBA)-initiated breast cancer in rats. The …

Aflatoxin B1 and M1: Biological properties and their involvement in cancer development

S Marchese, A Polo, A Ariano, S Velotto, S Costantini… - Toxins, 2018 - mdpi.com
effects of AFB1 on miRNA expression were investigated during the initiation phase of
carcinogenesis using liver tissues and blood from F344 rats exposed to AFB1 for 4 weeks. These …

Inhibitory effects of triterpenoid betulin on inflammatory mediators inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-alpha, interleukin-6, and …

J Yu, M Li, D Zhan, C Shi, L Fang, C Ban… - Pharmacognosy …, 2020 - phcog.com
… We observed tumor development in all DMH‑treated rats. … in the colon and liver tissues of
DMH‑treated rats (P < 0.05). On … in initiation, promotion, and progression of colon cancer.[43] …

… on growth performance, plasma biochemical parameters, fish composition, immune responses, liver histology, and immune and apoptosis-related genes expression …

X Tan, Z Sun, Q Liu, H Ye, C Zou, C Ye, A Wang… - Fish & shellfish …, 2018 - Elsevier
… , growth promotion, appetite stimulation, hepatoprotective … in rats fed high lipid diets-induced
nonalcoholic fatty liver … in order to initiate immune tolerance to the GBE itself, and the higher …

Effects of anthocyanins on the prevention and treatment of cancer

BW Lin, CC Gong, HF Song… - British journal of …, 2017 - Wiley Online Library
… the promotion of the expressions of ARE-regulated phase II … -regulated, while the expressions
of eukaryotic initiation factor … of Bcl-2 expression at the translational level Rats treated with …